I-kappa B Proteins

Synonyms

I kappa B

I kappa B Proteins

I-kappa B

IkB DNA Binding Proteins

IkB DNA-Binding Proteins

A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.