Insulysin

Synonyms

Enzyme, Insulin-Degrading

Insulin Degrading Enzyme

Insulin Protease

Insulin Proteinase

Insulin-Degrading Enzyme

Insulinase

Protease, Insulin

Proteinase, Insulin

An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides. It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur J Biochem 1994;223:1-5) EC 3.4.24.56.