Interferon Regulatory Factor-3
Synonyms
IFN Regulatory Factor 3
IFN-Regulatory Factor 3
IRF 3 Transcription Factor
IRF-3 Transcription Factor
Interferon Regulatory Factor 3
Transcription Factor, IRF-3
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.