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L Leucine Dehydrogenase

An octameric enzyme belonging to the superfamily of amino acid Dehydrogenases. Leucine Dehydrogenase catalyzes the reversible oxidative Deamination of L-Leucine, to 4-methyl-2-oxopentanoate (2-ketoisocaproate) and Ammonia, with the corresponding reduction of the cofactor NAD+.