Laron Syndrome

Synonyms

Dwarfism II, Pituitary

Dwarfism IIs, Pituitary

Dwarfism, Laron

GH Resistance, Primary

Growth Hormone Insensitivity Syndrome

Growth Hormone Receptor Defect

Growth Hormone Receptor Deficiency

Laron Dwarfism

Laron Type Dwarfism I

Pituitary Dwarfism II

Pituitary Dwarfism IIs

Primary GH Resistance

Primary Growth Hormone Resistance

Severe GH Insensitivity

Syndrome, Laron

An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.