Leukocyte-Adhesion Deficiency Syndrome
Synonyms
Deficiency Syndrome, Leukocyte Adhesion
Deficiency Syndrome, Leukocyte-Adhesion
Deficiency Syndromes, Leukocyte-Adhesion
Leukocyte Adhesion Deficiency Syndrome
Leukocyte-Adhesion Deficiency Syndromes
Syndrome, Leukocyte-Adhesion Deficiency
Syndromes, Leukocyte-Adhesion Deficiency
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.