Lipoproteins, HDL

Synonyms

HDL Lipoproteins

Heavy Lipoproteins

High Density Lipoproteins

High-Density Lipoproteins

Lipoproteins, Heavy

Lipoproteins, High-Density

alpha Lipoproteins

alpha-1 Lipoprotein

alpha-Lipoproteins

A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.