Microscopy, Interference

Synonyms

Interference Microscopy

Interference Reflection Microscopy

Interferometry, Microscopic

Microinterferometry

Microscopic Interferometry

Microscopy, Differential Interference Contrast

Microscopy, Interference Reflection

Microscopy, Nomarski Interference Contrast

Reflection Microscopy, Interference

The science and application of a double-beam transmission interference microscope in which the illuminating light beam is split into two paths. One beam passes through the specimen while the other beam reflects off a reference mirror before joining and interfering with the other. The observed optical path difference between the two beams can be measured and used to discriminate minute differences in thickness and refraction of non-stained transparent specimens, such as living cells in culture.