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N Nitrosodimethylamine Demethylase

An Ethanol-inducible Cytochrome P450 enzyme that metabolizes several precarcinogens, Drugs, and Solvents to reactive metabolites. Substrates include alcohol; Nitrosamines; Benzene; Urethane; and other low Molecular Weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.