Neurofibromin 1
Synonyms
NF 1 Protein
NF-1 Protein
NF1 GAP Related Protein
NF1 GRP
NF1 Protein
NF1-GAP-Related Protein
Neurofibromatosis Type 1 Gene Product
Neurofibromatosis Type 1 Protein
Neurofibromin
A protein found most abundantly in the nervous system. Defects or deficiencies in this protein are associated with NEUROFIBROMATOSIS 1, Watson syndrome, and LEOPARD syndrome. Mutations in the gene (GENE, NEUROFIBROMATOSIS 1) affect two known functions: regulation of ras-GTPase and tumor suppression.