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P protein, Glycine Decarboxylase

A Pyridoxal Phosphate dependent enzyme that catalyzes the Decarboxylation of Glycine with the Transfer of an aminomethyl group to the Lipoic Acid moiety of the Glycine Decarboxylase Complex H-Protein. Defects in P-protein are the cause of Non-ketotic Hyperglycinemia. It is one of four subunits of the Glycine Decarboxylase Complex.