Patch-Clamp Techniques

Synonyms

Patch Clamp Technics

Patch Clamp Techniques

Patch-Clamp Technic

Patch-Clamp Technics

Patch-Clamp Technique

Recording, Whole-Cell

Recordings, Whole-Cell

Technic, Patch-Clamp

Technic, Voltage-Clamp

Technics, Patch-Clamp

Technics, Voltage-Clamp

Technique, Patch-Clamp

Technique, Voltage-Clamp

Techniques, Patch-Clamp

Techniques, Voltage-Clamp

Voltage Clamp Technics

Voltage Clamp Techniques

Voltage-Clamp Technic

Voltage-Clamp Technics

Voltage-Clamp Technique

Voltage-Clamp Techniques

Whole Cell Recording

Whole-Cell Recording

Whole-Cell Recordings

An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.