Proteasome Endopeptidase Complex
Synonyms
20S Proteasome
Complex, Multicatalytic Endopeptidase
Complex, Proteasome Endopeptidase
Endopeptidase Complex, Multicatalytic
Endopeptidase Complex, Proteasome
Ingensin
Macropain
Macroxyproteinase
Multicatalytic Endopeptidase Complex
Multicatalytic Proteinase
Prosome
Proteasome
Proteasome, 20S
Proteinase, Multicatalytic
A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.