Protein Kinase C-alpha
Synonyms
PKC alpha Serine Threonine Kinase
PKC-alpha Serine-Threonine Kinase
Protein Kinase C alpha
Protein Kinase C(alpha)
Serine-Threonine Kinase, PKC-alpha
A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.