Protein Kinase C
Synonyms
Calcium Activated Phospholipid Dependent Kinase
Calcium Phospholipid Dependent Protein Kinase
Calcium Phospholipid-Dependent Protein Kinase
Calcium-Activated Phospholipid-Dependent Kinase
PKC Serine Threonine Kinase
PKC Serine-Threonine Kinase
Phospholipid Sensitive Calcium Dependent Protein Kinase
Phospholipid-Dependent Kinase, Calcium-Activated
Phospholipid-Sensitive Calcium-Dependent Protein Kinase
Protein Kinase M
Serine-Threonine Kinase, PKC
An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.