Proto-Oncogene Proteins c-abl

Synonyms

Products, abl Proto-Oncogene

Proteins abl, Proto-Oncogene

Proto Oncogene Proteins abl

Proto Oncogene Proteins c abl

Proto-Oncogene Products, abl

Proto-Oncogene Proteins abl

Proto-Oncogene Proteins, abl

abl Proto Oncogene Products

abl Proto Oncogene Proteins

abl Proto-Oncogene Products

abl Proto-Oncogene Proteins

abl, Proto-Oncogene Proteins

c abl Proteins

c-abl Proteins

c-abl, Proto-Oncogene Proteins

Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.