PTEN Phosphohydrolase

Synonyms

MMAC1 Protein

Mutated In Multiple Advanced Cancers 1 Protein

PTEN Phosphatase

PTEN Protein

PTEN Protein Phosphatase

Phosphatase and Tensin Homologue on Chromosome Ten Protein

Phosphatase, PTEN

Phosphatase, PTEN Protein

Phosphohydrolase, PTEN

Protein Phosphatase, PTEN

A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION.