Pteroylpolyglutamic Acids

Synonyms

Acids, Pteroylpolyglutamic

Folate Polyglutamates

Folates, Polyglutamate

Polyglutamate Folates

Polyglutamates, Folate

Pteroylpolyglutamates

Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays.