Pyruvate Decarboxylase
Synonyms
2 Oxo Acid Carboxy Lyase
2-Oxo Acid Carboxy-Lyase
Acid Carboxy-Lyase, 2-Oxo
Carboxy-Lyase, 2-Oxo Acid
Carboxylase, alpha-Ketoacid
Decarboxylase, Pyruvate
Decarboxylase, Pyruvic
Pyruvic Decarboxylase
alpha Carboxylase
alpha Ketoacid Carboxylase
alpha-Carboxylase
alpha-Ketoacid Carboxylase
Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.