RNA, Small Interfering

Synonyms

Hairpin RNA, Short

Hairpin RNA, Small

Interfering RNA, Short

Interfering RNA, Small

Piwi Interacting RNA

Piwi-Interacting RNA

RNA, Piwi Interacting

RNA, Piwi-Interacting

RNA, Scan

RNA, Short Hairpin

RNA, Short Interfering

RNA, Small Hairpin

RNA, Small Scan

Repeat Associated siRNA

Repeat-Associated siRNA

Scan RNA

Scan RNA, Small

Short Hairpin RNA

Short Interfering RNA

Small Hairpin RNA

Small Interfering RNA

Small Scan RNA

Trans Acting siRNA

Trans-Acting siRNA

piRNA

scnRNA

shRNA

siRNA

siRNA, Repeat Associated

siRNA, Repeat-Associated

siRNA, Trans Acting

siRNA, Trans-Acting

tasiRNA

Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.