Squalene Monooxygenase
Synonyms
Epoxidase, Squalene
Monooxygenase, Squalene
Squalene Epoxidase
Squalene Monooxygenase (2,3-Epoxidizing)
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.