src-Family Kinases

Synonyms

Kinases, src

Kinases, src Protein-Tyrosine

Kinases, src Tyrosine

Protein-Tyrosine Kinases, src

Tyrosine Kinases, src

Tyrosine Kinases, src-Family

src Family Kinases

src Family Tyrosine Kinases

src Kinases

src Protein-Tyrosine Kinases

src Tyrosine Kinases

src-Family Tyrosine Kinases

A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.

See Also
src Homology Domains