Thiorphan

Synonyms

(3-Mercapto-2-benzylpropionyl)glycine

Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)-

Thiorphan, (R)-Isomer

Thiorphan, (S)-Isomer

Tiorphan

A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.