v src Protein pp60

A Tyrosine-Specific Protein Kinase encoded by the v-src Oncogene of Rous sarcoma virus. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal Tyrosine Phosphorylation site at position 527, and the attachment of pp60(v-src) to the Plasma Membrane which is accomplished by myristylation of its N-terminal Glycine.