Vaccines, DNA

Synonyms

DNA Vaccines

DNA Vaccines, Naked

DNA Vaccines, Recombinant

Naked DNA Vaccines

Nucleic Acid Vaccines

Polynucleotide Vaccines

Recombinant DNA Vaccines

Vaccines, Naked DNA

Vaccines, Nucleic Acid

Vaccines, Polynucleotide

Vaccines, Recombinant DNA

Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.