ADAM17 Protein


ADAM 17 Protein


ADAM-17 Protein

Antigen, CD156b

CD156b Antigen

Convertase, TNF-alpha

Disintegrin and Metalloproteinase Domain Containing Protein 17

Disintegrin and Metalloproteinase Domain-Containing Protein 17

TACA (Enzyme)

TACE (Enzyme)

TNF alpha Convertase

TNF alpha Converting Enzyme

TNF-alpha Convertase

TNF-alpha Converting Enzyme

Tumor Necrosis Factor Alpha Convertase

Tumor Necrosis Factor alpha Converting Enzyme

Tumor Necrosis Factor-alpha Convertase

Tumor Necrosis Factor-alpha Converting Enzyme

A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS.