AlkB Homolog 4, Lysine Demethylase


Alkylated DNA Repair Protein AlkB Homolog 4

Alpha Ketoglutarate Dependent Dioxygenase Alkb Homolog 4

Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4

A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation.