Amiloride

Synonyms

Alphapharm Brand of Amiloride Hydrochloride

Amidal

Amiduret Trom

Amiloberag

Amiloride Hydrochloride

Amiloride Hydrochloride, Anhydrous

Amrad Brand of Amiloride Hydrochloride

Anhydrous Amiloride Hydrochloride

Berolina Brand of Amiloride Hydrochloride

Cahill May Roberts Brand of Amiloride Hydrochloride

Douglas Brand of Amiloride Hydrochloride

Hydrochloride, Amiloride

Hydrochloride, Anhydrous Amiloride

Kaluril

Merck Brand of Amiloride Hydrochloride

Merck Sharp & Dohme Brand of Amiloride Hydrochloride

Midamor

Midoride

Modamide

Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-

Trom, Amiduret

Trommsdorff Brand of Amiloride Hydrochloride

A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)