Antigens, CD80

Synonyms

Antigen, B7 1

Antigen, B7-1

B Cell Activation Antigen

B-Cell Activation Antigen

B7 1 Antigen

B7 1 Costimulatory Molecule

B7 1 Ligand

B7-1 Antigen

B7-1 Costimulatory Molecule

B7-1 Ligand

CD80 Antigen

CD80 Antigens

Costimulatory Molecule, B7-1

Ligand, B7-1

A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.