Apoptotic Protease-Activating Factor 1


Apaf 1 Protease Activating Factor

Apaf-1 Protease-Activating Factor

Apoptotic Peptidase Activating Factor 1

Apoptotic Protease Activating Factor 1

Protease-Activating Factor, Apaf-1

A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.