Apoptotic Protease-Activating Factor 1
Apaf 1 Protease Activating Factor
Apaf-1 Protease-Activating Factor
Apoptotic Peptidase Activating Factor 1
Apoptotic Protease Activating Factor 1
Protease-Activating Factor, Apaf-1
A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.