ATXN3 Protein

Ataxin 3

Ataxin 3 Protein

Ataxin-3 Protein

Machado Joseph Disease Protein

Machado-Joseph Disease Protein

SCA3 Protein

Spinocerebellar Ataxia 3 Protein

A deubiquitinating enzyme of the ATAXINS family. It functions in protein homeostasis, GENETIC TRANSCRIPTION; CYTOSKELETON regulation, and MYOGENESIS. CAG TRINUCLEOTIDE REPEAT EXPANSION in the Ataxin-3 gene coding region is associated with spinocerebellar ataxia-3 (MACHADO-JOSEPH DISEASE).