Carboxypeptidase B2
Synonyms
Arginine Carboxypeptidase
Carboxypeptidase B2, Plasma
Carboxypeptidase R
Carboxypeptidase U
Plasma Carboxypeptidase B2
Plasma Procarboxypeptidase B
Procarboxypeptidase U
Thrombin Activatable Fibrinolysis Inhibitor
Thrombin-Activatable Fibrinolysis Inhibitor
Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.