Caspase 2


Caspase 2 Subunit p12

Caspase 2 Subunit p13

Caspase 2 Subunit p18


ICH 1 Protease

ICH-1 Protease

Pro Caspase 2


Procaspase 2


A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.