Cervical Intraepithelial Neoplasia

Synonyms

Cervical Intraepithelial Neoplasia, Grade III

Cervical Intraepithelial Neoplasm

Cervical Intraepithelial Neoplasms

Intraepithelial Neoplasia, Cervical

Intraepithelial Neoplasm, Cervical

Intraepithelial Neoplasms, Cervical

Neoplasia, Cervical Intraepithelial

Neoplasm, Cervical Intraepithelial

Neoplasms, Cervical Intraepithelial

A malignancy arising in uterine cervical epithelium and confined thereto, representing a continuum of histological changes ranging from well-differentiated CIN 1 (formerly, mild dysplasia) to severe dysplasia/carcinoma in situ, CIN 3. The lesion arises at the squamocolumnar cell junction at the transformation zone of the endocervical canal, with a variable tendency to develop invasive epidermoid carcinoma, a tendency that is enhanced by concomitant human papillomaviral infection. (Segen, Dictionary of Modern Medicine, 1992)