Cytochrome P-450 CYP1B1

Synonyms

Cytochrome P 450 CYP1B1

Cytochrome P450 CYP1B1

Cytochrome P450, Family 1, Subfamily B, Polypeptide 1

Cytochrome P4501B1

P450 CYP1B1, Cytochrome

A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.