DNA Polymerase I

Synonyms

DNA Dependent DNA Polymerase I

DNA Pol I

DNA Polymerase alpha

DNA-Dependent DNA Polymerase I

Klenow Fragment

Polymerase I, DNA

Polymerase alpha, DNA

A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair. EC 2.7.7.7.