DNA Topoisomerase IV


Topo IV

Topoisomerase IV

Topoisomerase IV Subunit A

Topoisomerase IV Subunit B

Topoisomerase IV, DNA

parC Gene Product

parC Gene Product, Topo IV

parC Protein

parE Gene Product

parE Gene Product, Topo IV

parE Protein

A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.