B61 Secreted Protein, Endothelium


Eck Ligand

Eck RPTK Ligand

Endothelium Secreted Protein B61

Ephrin A1

Epl1 Protein

LERK 1 Protein

LERK-1 Protein

Ligand, Eck

RPTK Ligand, Eck

An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.