(5-L-Glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)
gamma Glutamylamine Cyclotransferase
An enzyme that catalyzes the synthesis of pyroglutamate from a gamma-glutamyl-amino acid, also releasing the free amino acid. The enzyme acts on derivatives of glutamate, 2-aminobutyrate, alanine and glycine. The enzyme has been proposed to have a role in a gamma-glutamyl cycle for amino acid transport into cells in the intestines. EC 188.8.131.52.