Gangliosidoses, GM2


G(M2) Gangliosidoses

GM2 Gangliosidose

GM2 Gangliosidoses

GM2 Gangliosidosis

GM2, Gangliosidoses

Gangliosidose, GM2

Gangliosidoses GM2

Gangliosidosis, GM2

A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASES system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS.