Gene Products, nef

Synonyms

3' orf Protein

3'-orf Protein

Gene Product, nef

nef Gene Product

nef Gene Products

nef Protein

Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.