Heparin-binding EGF-like Growth Factor
Synonyms
Diphtheria Toxin Receptor
Diphtheria Toxin Receptors
HB EGF
HB EGF Precursor
HB-EGF
HB-EGF Precursor
HB-EGF, Short Form
Heparin binding EGF like Growth Factor
Heparin binding Epidermal Growth Factor like Growth Factor Precursor Protein
Heparin-binding EGF-like Growth-Factor
Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein
Receptor, Diphtheria Toxin
Receptors, Diphtheria Toxin
SF HB EGF
SF HB-EGF
Short Form HB EGF
Short Form HB-EGF
Toxin Receptor, Diphtheria
Toxin Receptors, Diphtheria
An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.