Histamine H1 Antagonists, Non-Sedating


Antihistamines, Second Generation

H1 Antihistamines, Non Sedating

H1 Antihistamines, Non-Sedating

Histamine H1 Antagonists, Non Sedating

Non-Sedating H1 Antihistamines

Second Generation Antihistamines

Second Generation H1 Antagonists

Third Generation H1 Antagonists

A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.