Acidosis, Renal Tubular Type IV

Hypoaldosteronism, Hyporeninemic

Hyporeninemic Hypoaldosteronism

Renal Tubular Acidosis, Type IV

Type IV Renal Tubular Acidosis

A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS.