Immunoglobulin Fc Fragments
Synonyms
Fc Fragment Immunoglobulins
Fc Fragment, Immunoglobulin
Fc Fragments
Fc Fragments, Immunoglobulin
Fc Immunoglobulins
Fragment Immunoglobulins, Fc
Immunoglobulin Fc Fragment
Immunoglobulins, Fc
Immunoglobulins, Fc Fragment
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
See Also