In Situ Nick-End Labeling
Synonyms
In Situ Nick End Labeling
In Situ Nick End Labelling
In Situ Nick End-Labeling
In Situ Nick End-Labelling
In Situ Nick-End Labelling
Nick End Labeling, In Situ
Nick End Labelling, In Situ
Nick End-Labeling, In Situ
Nick End-Labelling, In Situ
Nick-End Labeling, In Situ
Nick-End Labelling, In Situ
TUNEL
An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
See Also