Glycoprotein Ia IIa
Late Antigen-2, Very
Platelet Membrane Glycoprotein Heterodimer Ia IIa
Platelet Membrane Glycoprotein Heterodimer Ia-IIa
Very Late Antigen 2
Very Late Antigen-2
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.