MPTP Poisoning


MPTP Induced Degeneration of the Striatum

MPTP Induced Parkinsonism

MPTP Neurotoxicity Syndrome

MPTP Neurotoxicity Syndromes

MPTP-Induced Degeneration of the Striatum

MPTP-Induced Parkinsonism

Neurotoxicity Syndrome, MPTP

Neurotoxicity Syndromes, MPTP

Parkinsonism, MPTP-Induced

Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Poisoning, MPTP

A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)