Multiple System Atrophy


Atrophies, Multisystem

Atrophies, Multisystemic

Atrophy, Multiple System

Atrophy, Multisystem

Atrophy, Multisystemic

Multiple System Atrophies

Multiple System Atrophy Syndrome

Multisystem Atrophies

Multisystem Atrophy

Multisystemic Atrophies

Multisystemic Atrophy

A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)