Myosin-Light-Chain Kinase
Synonyms
ATP:myosin-light-chain O-phosphotransferase
Kinase, Myosin
Kinase, Myosin-Light-Chain
LCK, Myosin
Myosin Kinase
Myosin LCK
Myosin Light Chain Kinase
Myosin Regulatory Light Chain Kinase
Myosin Regulatory Light-Chain Kinase
An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.